Predictive factors for resistance to Helicobacter pylori eradication therapy as determined by logistic regression analysis
| All patients (n=420) | Selected patients (n=175*) | |||
| Factors | OR (95% CI) | p Value | OR (95% CI) | p Value |
| Age (each incremental year) | 2.39 (0.43 to 13.83) | 0.323 | 4.63 (0.23 to 111.91) | 0.329 |
| Sex (male) | 2.04 (1.15 to 3.65) | 0.015 | 2.27 (0.89 to 5.93) | 0.087 |
| H pylori status (negative) | 31.73 (12.89 to 91.49) | <0.0001 | 24.29 (5.12 to 189.15) | 0.0003 |
| Location (proximal or multiple) | 2.63 (1.48 to 4.73) | 0.001 | 1.18 (0.44 to 3.11) | 0.742 |
| Endoscopic type (non-superficial) | 2.32 (1.28 to 4.18) | 0.005 | 2.33 (0.73 to 7.47) | 0.152 |
| Clinical stage (II1 or more) | 2.91 (1.28 to 6.53) | 0.0097 | 2.69 (0.69 to 10.89) | 0.156 |
| Depth of invasion by EUS (≥SM) | 6.02 (2.12 to 19.13) | 0.0012 | ||
| t(11;18)/API2-MALT1 (positive) | 44.03 (7.89 to 388.27) | <0.0001 | ||
↵* Patients who underwent both EUS and investigation for t(11;18).
EUS, endoscopic ultrasonography; ≥SM, submucosa or beyond.