Results of fixed effects meta-analysis by CRM criteria
| Method | HR (95% CI) | Test of effect | Test of heterogeneity | I2 value |
| RCPath criteria (UK) | 1.45 (1.27 to 1.66) | <0.0001 | 0.003 | 72.70% |
| CAPcriteria (USA) | 2.61 (1.90 to 3.59) | <0.0001 | 0.33 | 9.90% |
| Overall | 1.58 (1.40 to 1.79) | <0.0001 | <0.001 | 74.80% |