Table 7

Logistic regression analyses of Crohn's disease patients with work disability as the dependent variable

Variable	n	Univariate			Multivariate
Variable	n	OR	95% CI	p Value	OR	95% CI	p Value
Gender
Male (ref)	81	1			1
Female	79	2.22	1.05 to 4.67	0.04	2.41	1.07 to 5.40	0.03
Age at diagnosis
≤40 years (ref)	124	1			1
>40 years	36	2.13	0.95 to 4.78	0.07	1.99	0.82 to 4.80	0.13
Education level at diagnosis
Missing=14
<12 years (ref)	87	1
>12 years	59	1.27	0.60 to 2.69	0.53
Smoking at diagnosis
Missing=2
Non-smoker (ref)	88	1
Smoker	70	1.67	0.81 to 3.45	0.17
SR or CRP at diagnosis
Missing=5
≤30 (ref)	49	1
>30	106	1.75	0.76 to 4.05	0.19
Disease localisation at diagnosis
L1 or L4 (ref)	49	1
L2	70	0.63	0.27 to 1.47	0.28
L3	41	0.92	0.36 to 2.32	0.85
Disease behaviour at diagnosis
B1 (ref)	97	1
B2	45	0.82	0.36 to 1.9	0.65
B3	18	0.82	0.25 to 2.73	0.75
Abscess and/or fistula at diagnosis
Missing=10
Yes (ref)	20	1
No	130	1.02	0.34 to 3.03	0.97
Steroid treatment at diagnosis
Missing=2
No (ref)	68	1
Yes	90	1.40	0.66 to 2.97	0.38
Steroid treatment at 1-year follow-up
Missing=4
No (ref)	102	1			1
Yes	54	4.30	2.00 to 9.28	<0.001	4.33	1.96 to 9.59	<0.001
Number of relapses during 1st year
Missing=4
None (ref)	75	1
1–2	69	1.63	0.76 to 3.52	0.21
>2	12	1.33	0.32 to 5.54	0.69
Resection before 1-year follow-up
No (ref)	130	1
Yes	30	0.93	0.37 to 2.38	0.88
Mucosal healing at 1-year follow-up
Missing=43
Yes (ref)	56	1
No	61	1.20	0.50 to 2.84	0.69
ASCA
Missing=13
Negative (ref)	103	1
Positive	43	1.13	0.50 to 2.58	0.77

No work disability, n=121; work disability, n=39.
ASCA, anti-Saccromyces cerevisiae antibodies; Ref, reference category; WD, work disability because IBD (applied for or granted rehabilitation benefits or disability pension).