Azathioprine intolerant (n= 35) | Azathioprine tolerant (n= 106) | |
---|---|---|
Requiring surgery (%) | 13 (37.1) | 55 (51.8) |
% stricture/fistula | 17 (48.6) | 63 (59.4) |
Extensive disease | 3/30 (10) | 11/92 (12.0) |
Disease activity:- | 19/34 (55.9) | 76/96 (79.2) |
- Remission (HBI < 5) | 7/34 (20.6) | 17/96 (17.7) |
- Mild disease (HBI 5–7) | 8/34 (23.5) | 3/96 (3.1) |
- Moderate disease (HBI 8–16) | 0/34 (0) | 0/96 (0) |
- Severe disease (HBI > 16) | 7 (20.0) | 2 (1.9 |
Steroid dependent | 9 (25.7) | 13 (12.3) |
Monoclonal antibody |