Cohorts | Discovery set: case–control | Derivation set: case–control | Validation set 1: nested case–control | Validation set 2: prospective | Test set: case–control | |||||
---|---|---|---|---|---|---|---|---|---|---|
Cases | Controls | Cases | Controls | Cases | Controls | CDA | No CDA | Cases | Controls | |
Italy | 695 | 635 | 693 | 635 | 99 | 219 | ||||
The Netherlands | 535 | 586 | 535 | 583 | 61 | 175 | ||||
Poland | 235 | 270 | 236 | 269 | 50 | 67 | ||||
Spain 1 | 242 | 171 | 242 | 170 | 34 | 122 | ||||
Spain 2 | 268 | 160 | 269 | 159 | 33 | 125 | ||||
UK | 700 | 1000 | 700 | 999 | ||||||
Sweden | 306 | 1403 | ||||||||
Non-Hispanic white American | 70 | 1174 | ||||||||
Sub-total | 2675 | 2822 | 2675 | 2815 | 306 | 1403 | 70 | 1174 | 277 | 708 |
Total | 5497 | 5490 | 1709 | 1244 | 985 |
CDA, coeliac disease autoimmunity; SNP, single-nucleotide polymorphism.