Pregnancy and fetal outcomes with thiopurine and allopurinol co-therapy
| Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 | Case 7 | Case 8 | |
|---|---|---|---|---|---|---|---|---|
| Diagnosis | UC | UC | UC | UC | UC | UC | UC | Crohns |
| Dose thiopurine/allopurinol | AZA 50 mg, Allo 100 mg | AZA 25 mg 5d / 50 mg 2d, Allo 10 0mg | AZA 25 mg 5d / 50 mg 2d, Allo 100 mg | AZA 50 mg, Allo 200 mg | 6MP 50 mg 5d, Allo 100 mg | 6MP 50 mg 5d, Allo 100 mg | 6MP 25 mg 3d, Allo 100 mg | 6MP 50 mg 6d, Allo 100 mg |
| Duration of pre-pregnancy co-therapy (months) | 6 | 19 | 1 | 12 | 14 | 6 | 15 | 24 |
| Age at pregnancy (years) | 21 | 24 | 34 | 31 | 32 | 36 | 32 | 29 |
| Number of flares in pregnancy | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Gestation at delivery (weeks) | 41 | 38 +1 | 39 +4 | 40 +3 | 38 | 39 | 34 | 38 |
| Mode of delivery | SVD | C-section | C-section | SVD | SVD | SVD | C-section | C-section |
| Fetal birth weight | 3.5 kg | 2.94 kg | 3.42 kg | 3.95 kg | 3.75kg | 3.0 kg | 2.91 kg | 3.51 kg |