Details of the mutations in the RT region identified at the baseline
| Mutations detected in| RT region (amino acid changes) | Besifovir 90 mg, n=36 (%) | Besifovir 150 mg, n=39 (%) | Entecavir 0.5 mg, n=39 (%) |
|---|---|---|---|
| rt163 (ile→val) | 1 (11) | 1 (20) | 0 (0) |
| rt181 (ala→thr/ val/ ser) | 0 (0) | 0 (0) | 1 (20) |
| rt207 (val→ile/ leu) | 0 (0) | 1 (20) | 1 (20) |
| rt214 (val→ala) | 0 (0) | 0 (0) | 3 (30) |
| rt222 (ala→thr) | 0 (0) | 3 (60) | 3 (30) |
| rt229 (leu→val) | 3 (33) | 0 (0) | 0 (0) |
| rt238 (asn→thr/ asp) | 5 (56) | 1 (20) | 2 (20) |
| rt84 (val→met) | 0 (0) | 0 (0) | 1 (20) |
| rt85 (ser→ala) | 0 (0) | 0 (0) | 1 (20) |
| Total 9 (25) | Total 6 (12.82) | Total 10 (24.64) |
RT, reverse transcriptase.