Abstract PWE-161 Table 1
Mean (SD)HV (n = 11)FC (n = 23)IBS-C (n = 20)P value
WGT (h)30.4108.2*,** 71.4*<0.0001
Fasting small bowel water content (SBWC) (ml)83 (64)114 (97) ** 57 (61)0.0383
Fasting AC (ml)193 (84)314 (100) *,** 219 (66)0.0002
AC volume 2h post ingestion of MCG (ml)357 (153)597 (170)376 (163)<0.0001
MI 2h post ingestion of MCG (s)80.2 (48.1)28.3 (35.1) *,** 56.4 (42.9)0.0044
Time to first bowel movement (min)117.3 (62.4)588 (1034) *,** 97.3 (72)0.0001
Bowel frequency on study day7.8 (2.7)3.9 (4.1) *,** 7.8 (3.0)<0.0001
Hypersensitivy Index (l-1)5.7 (4.9)12.3 (6.6) * 16.6 (14) * 0.0133
  • * p < 0.05 compared to HV

  • ** p < 0.05 compared to IBS-C.