Table 3

Adverse events with fatal outcome (n=1587)

	Patient 1	Patient 2	Patient 3	Patient 4	Patient 5	Patient 6	Patient 7
Age	52	51	50	55	60	66	56
Gender	Male	Female	Female	Male	Male	Male	Male
Fibrosis stage	F4	F4	F4	F3	F4	F4	F4
BSL VL	1 200 000	2 387 203	389 340	3 180 000	1 430 000	977 100	2 502 935
Last obs. VL	Undetectable	Undetectable	20	570	Undetectable	–	–
Dates of TVR treatment	July 2011 to September 2011	December 2011 to February 2012	January 2012 to April 2012	September 2011 to December 2011	November 2011 to February 2012	May 2012 to July 2012	April 2012 to July 2012
Date of death	4 weeks after TVR d/c	2 weeks after TVR d/c	4 weeks after TVR d/c	30 weeks after TVR d/c	4 weeks after TVR d/c	24 weeks after TVR d/c	8 weeks after TVR d/c
Adverse event	Anaemia, dehydration, hepatic failure, hepatorenal syndrome, hyper-catabolism, keto-acidosis, multi-organ failure	Ischaemic colitis, septic shock, multi-organ failure	Hepatic failure, bone marrow failure, multi-organ failure	Anaemia, hepatic neoplasm malignant, intra-abdominal haemorrhage, pneumonia	Anaemia, oesophageal variceal haemorrhage	Diarrhoea, vomit, hypotension, septic shock, coma	Anaemia, fatigue, pneumonia
Causality	Possibly related	Related	Unlikely related	Unlikely/not related	Unlikely related	Not related	Unlikely related
Medical history	Diabetes		Low platelets (74 000)			Neutropenia (830 cells/mm³)