Adverse events of the study patients
| SEQ (n=179) | QUAD (n=178) | p Value | |
|---|---|---|---|
| Nausea | 1 (0.6) | 6 (3.4) | 0.121 |
| Vomiting | 2 (1.2) | 4 (2.3) | 0.685 |
| Increased stool frequency | 1 (0.6) | 3 (1.7) | 0.623 |
| Abdominal pain | 1 (0.6) | 3 (1.7) | 0.623 |
| Skin rash | 4 (2.3) | 4 (2.3) | 1.0 |
| Taste disturbance | 3 (1.7) | 2 (1.1) | 0.685 |
| Dizziness | 1 (0.6) | 3 (1.7) | 0.623 |
| Headache | 1 (0.6) | 2 (1.1) | 1.0 |
| Insomnia | 0 (0) | 1 (0.6) | 1.0 |
| Fatigue | 0 (0) | 1 (0.6) | 1.0 |
| Total events | 14 (8.1) | 29 (16.7) | 0.032 |
Data are n (%).
QUAD, modified quadruple therapy; SEQ, sequential therapy.