Demographics, histological stage and endoscopic characteristics of AFI+ areas for patients included in training and validation cohorts
| Training cohort | Validation cohort | p Value | |
|---|---|---|---|
| Variables | |||
| Number of patients | 157 | 46 | N/A |
| Male: female (%) | 79:21 | 93:7 | 0.06 |
| Mean age (range) | 66.4 (35–87) | 68.7 (35–84) | 0.23 |
| Mean length of BO in cm (range) | 7.3 (2–17) | 7.6 (3–18) | 0.85 |
| Histological diagnosis | |||
| NDBO | 99 (63%) | 22 (56.4%) | 0.24 |
| LGD | 21 (13.4%) | 8 (20.5%) | |
| HGD | 24 (15.3%) | 3 (7.7%) | |
| EC | 13 (8.3%) | 6 (15.4%) | |
| Endoscopic features | |||
| Number of AFI+ areas | 229 | 108 | N/A |
| AFI+ areas visible on HRE | 28.4% | 21% | 0.15 |
| AFI+ areas with HGD/EC | 21.1% | 15.4% | 0.32 |
AFI, autofluorescence imaging; EC, early cancer; HGD, high-grade dysplasia; HRE, high-resolution endoscopy; LGD, low-grade dysplasia; NDBO, non-dysplastic Barrett's oesophagus.