Time period | N events in CD | Rate in CD per 1000 | Unadjusted HR | Adjusted HRa | |
---|---|---|---|---|---|
Before diagnosis | |||||
+1 year | 21 | 1.43 | 1.45 (0.93–2.24) | 1.62 (1.04–2.53) | |
within 1 year | 13 | 4.62 | 4.66 (2.68–8.10) | 4.69 (2.69–8.18) | |
After diagnosis | |||||
within 1 year | 6 | 2.28 | 2.33 (1.04–5.21) | 2.31 (1.03–5.19) | |
1–4 years | 19 | 2.12 | 2.14 (1.35–3.39) | 2.11 (1.39–3.35) | |
+ 5 years | 31 | 1.59 | 1.60 (1.11–2.31) | 1.63 (1.13–2.36) | |
↵a Adjusted for gender, calendar year; body mass index; smoking; Charlson index; socioeconomic status; Reference is controls group