Cox regression analysis of potential poor prognostic factors for patients with colorectal cancer
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| Variable | RR (95% CI) | p Value | RR (95% CI) | p Value |
| Age | 1.02 (0.99 to 1.05) | 0.13 | 1.02 (0.99 to 1.05) | 0.24 |
| Gender | ||||
| Male | 0.88 (0.45 to 1.73) | 0.70 | 0.78 (0.39 to 1.54) | 0.45 |
| Female | 1.00 | 1.00 | ||
| Location | ||||
| Colon | 0.57 (0.20 to 1.60) | 0.28 | ||
| Rectal | 1.00 | |||
| Grade | ||||
| High or moderate | 1.33 (0.66 to 2.68) | 0.43 | ||
| Low | 1.00 | |||
| TNM stage | ||||
| I | 0.06 (0.01 to 0.22) | <0.001 | 0.07 (0.16 to 0.27) | <0.001 |
| II | 0.19 (0.07 to 0.53) | 0.001 | 0.28 (0.09 to 0.80) | 0.017 |
| III | 0.53 (0.21 to 1.38) | 0.19 | 0.69 (0.26 to 1.81) | 0.45 |
| IV | 1.00 | 1.00 | ||
| SLC12A5 expression in tumour tissues | ||||
| High | 2.38 (1.21 to 4.66) | 0.01 | 2.30 (1.16 to 4.60) | 0.018 |
| Low | 1.00 | 1.00 | ||
RR, relative risk; The TNM Staging System is based on the extent of the tumor (T), the extent of spread to the lymph nodes (N), and the presence of metastasis (M).