Table 1

Crypt survival after pretreatment with probiotics

TreatmentCrypt survivalp Value
PBS control1.00±0.15
LGG (cultured/washed)1.98±0.23<0.01
Culturelle1.64±0.130.01
Bifidobacterium infantis 356241.09±0.180.37
  • Mice were given probiotics (LGG at 5×108 bacteria, Culturelle and B infantis at 1:500th capsule) for 3 days before irradiation with 12 Gy and killed at 84 h after irradiation. Jejunal crypt survival was assessed by bromodeoxyuridine incorporation. Mean±SEM crypt survival is presented as normalised to PBS control. p Value is compared with PBS control.

  • LGG, Lactobacillus rhamnosus GG; PBS, phosphate-buffered saline.