Characteristics of obese patients after gastric bypass and gastric banding and unoperated controls at time of fMRI scanning
| BMI-M | BAND | RYGB | p Values* | |
|---|---|---|---|---|
| n | 20 | 20 | 21 | |
| Age (years) | 39.1±2.3 (20.0–55.0) | 40.9±2.5 (22.0–59.0) | 43.5±2.0 (23.0–59.0) | 0.38 |
| Gender (Male:Female) | 3 : 17 | 1 : 19 | 4 : 26 | 0.57 |
| Postmenopausal women, n (%) | 5 (25%) | 5 (25%) | 6 (29%) | 0.96 |
| Ethnicity: European Caucasians, n (%) | 10 (50%) | 15 (75%) | 16 (76%) | 0.14 |
| Preoperative BMI (kg/m2) | n/a | 44.8 [41.9–49.2] (36.5–57.0) | 48.4 [40.7–58.0] (34.7–74.6) | 0.23 |
| Current BMI (kg/m2) | 35.4±1.9 (24.7–55.6) | 35.1±1.4 (25.3–49.2) | 35.3±1.7 (22.6–52.4) | 0.99 |
| Current height (m) | 1.64±0.02 (1.49–1.78) | 1.66±0.02 (1.53–1.79) | 1.66±0.02 (1.52–1.85) | 0.64 |
| Current weight (kg) | 97.0±3.1 (73.9–119.8) | 97.0±3.1 (73.9–119.8) | 98.1±4.9 (63.7–137.9) | 0.97 |
| Current body fat (%) | 42.1±2.2 (26.0–58.2) | 41.9±1.8 (23.3–54.7) | 41.3±1.9 (28.4–56.0) | 0.96 |
| Weight loss (% of preoperative weight) | n/a | 23.1 [14.5–29.3] (9.7–52.4) | 29.9 [23.4–36.5] (16.3–40.4) | 0.018 RYGB > BAND |
| Time since surgery (months) | n/a | 9.1 [5.2–19.2] (3.6–64.6) | 8.1 [5.9–11.5] (2.6–26.2) | 0.25 |
| Preoperative DM, n (%) | n/a | 2 (10%) | 10 (48%) | 0.02 RYGB > BAND |
| Current DM, n (%) | 2 (10%) | 0 (0%) | 3 (14%) | 0.23 |
| Preoperative obesity comorbidity score | n/a | 6.0 [4.5–6.0] (1.0–10.0) | 10.0 [6.6–11.5] (3.0–19.0) | <0.001 RYGB > BAND |
| Current obesity comorbidity score | 0.0 [0.0–5.0] (0.0–18.0) | 0.0 [0.5–2.0] (0.0–9.0) | 1.0 [0.8–3.0] (0.0–10.0) | 0.85 |
| Preoperative BED, n (%) | n/a | 4 (25%) | 4 (19%) | 1.00 |
| Current BED, n (%) | 2 (10%) | 2 (10%) | 1 (5%) | 0.78 |
Data included only for those subjects who had fMRI scanning. Data presented as mean±SEM or median [IQR] for data that are not normally distributed and (range).
*p Value for overall comparison between groups.
BAND, gastric banding; BED, binge eating disorder; BMI, body mass index; BMI-M, BMI-matched; DM, type 2 diabetes mellitus; n/a, not applicable; RYGB, gastric bypass.