Table 5

Number of screenees imaged by CTC, subsequent referrals for further testing, and ultimate detection for cancer, large polyp (10 mm+), medium-sized polyp (6–9 mm), any polyp or cancer, any adenoma or cancer and advanced neoplasia, split by age and sex

60–64 years65–69 years70–74 years75+ years
Number imaged by CTC
 Men56062527941
 Women45548924636
 Total1015111452577
Number (%) with suspected polyp or cancer on CTC
 Men227 (40.5)252 (40.3)131 (47.0)22 (53.7)
 Women134 (29.5)164 (33.5)77 (31.3)20 (55.6)
 Total361 (35.6)416 (37.3)208 (39.6)42 (54.5)
Number (%) with proven cancer
 Men25 (4.5)38 (6.1)19 (6.8)7 (17.1)
 Women14 (3.1)12 (2.5)8 (3.3)1 (2.8)
 Total39 (3.8)50 (4.5)27 (5.1)8 (10.4)
Number (%) with matched 10 mm+ polyp
 Men86 (15.4)91 (14.6)46 (16.5)4 (9.8)
 Women45 (9.9)43 (8.8)19 (7.7)6 (16.7)
 Total131 (12.9)134 (12.0)65 (12.4)10 (13.0)
Number (%) with matched 6–9 mm polyp
 Men27 (4.8)28 (4.5)14 (5.0)2 (4.9)
 Women14 (3.1)20 (4.1)9 (3.7)5 (13.9)
 Total41 (4.0)48 (4.3)23 (4.4)7 (9.1)
Number (%) with any matched polyp or cancer
 Men158 (28.2)180 (28.8)83 (29.7)15 (36.6)
 Women78 (17.1)89 (18.2)41 (16.7)13 (36.1)
 Total236 (23.3)269 (24.1)124 (23.6)28 (36.4)
Number (%) with any matched adenoma or cancer
 Men141 (25.2)159 (25.4)80 (28.7)15 (36.6)
 Women68 (14.9)78 (16.0)37 (15.0)14 (38.9)
 Total209 (20.6)237 (21.3)117 (22.3)29 (37.7)
Number (%) with advanced neoplasia
 Men115 (20.5)145 (23.2)69 (24.7)11 (26.8)
 Women58 (12.7)63 (12.9)32 (13.0)11 (30.6)
 Total173 (17.0)208 (18.7)101 (19.2)22 (28.6)
  • Percentages use the total number of screenees imaged by CTC of that sex and age category as the denominator.

  • Age, sex and individual's screening round were highly significant predictors of CTC detection rates in both univariate and multivariate analysis (table 6).

  • CTC, CT colonography.