Table 8

Screenee and institutional factors associated with detection rates following CTC, derived via a multilevel logistic regression model and expressed as ORs

VariableCrude ORp Value*Random effects model ORp Value*
Screenee factorsMen (vs women)1.86 (1.56 to 2.23)<0.0011.83 (1.50 to 2.23)<0.001
Screened for second time (vs first time)0.73 (0.60 to 0.87)<0.0010.75 (0.61 to 0.93)<0.001
Screened for third time (vs first time)0.46 (0.29 to 0.69)<0.0010.43 (0.26 to 0.70)<0.001
Age (per year increase)1.04 (1.02 to 1.06)<0.0011.04 (1.02 to 1.06)<0.001
Institutional factorsThree-dimensional review of images (vs primary two-dimensional)1.31 (1.07 to 1.60)0.0101.38 (1.02 to 1.95)0.023
Experience of radiologist (vs <300 cases)
High (1000+ cases)1.49 (1.16 to 1.94)0.0201.44 (1.02 to 2.04)0.038
Medium (300–999 cases)1.18 (0.90 to 1.54)0.231.22 (0.87 to 1.72)0.26
High workload (>175 cases per radiologist per annum, vs less than this)1.52 (1.22 to 1.89)0.0171.41 (1.02 to 1.93)0.032
Use of purgation combined with tagging (vs either alone)1.14 (0.95 to 1.38)0.161.12 (0.85 to 1.48)0.40
  • *Probablility value for the Wald z-score. Italic values are significant at the 5% level.

  • CTC, CT colonography.