Table 2

Number of mutations per individual microsatellite marker28

Microsatellite markerChromosomeTissueUntreated5-ASA low5-ASA highTQ lowTQ high
Gene Bank
TG2710B5.1SI epithelium1.13 (0.09)0.88 (0.08)1.06 (0.06)0.94 (0.10)0.94* (0.06)
AC098712SI tumour2.60 (0.31)2.00 (0)3.33 (0.99)1.22 (0.22)0.83 (0.17)
GA295G1SI epithelium1.56 (0.20)1.06 (0.10)1.33 (0.14)1.24 (0.16)1.18 (0.15)
AC083948SI tumour3.40 (0.31)3.20 (1.36)5.00 (1.13)1.56 (0.41)1.67 (0.42)
CT25CA273A3SI epithelium1.19 (0.10)0.88 (0.15)0.61† (0.12)0.81 (0.14)0.94 (0.13)
AC079442SI tumour2.40 (0.4)2.40 (0.98)5.33* (0.67)1.88 (0.70)1.17 (0.31)
A3317E4SI epithelium1.38 (0.15)1.18 (0.15)0.89 (0.20)0.94 (0.23)1.06 (0.13)
AC096777SI tumour1.10 (0.10)1.60 (0.60)1.67 (0.33)1.00 (0.33)1.17 (0.65)
A2717E4SI epithelium2.19 (0.21)1.94 (0.16)1.89 (0.18)1.81 (0.26)1.65 (0.21)
AC096777SI tumour2.50 (0.34)2.40 (0.40)3.83 (0.40)2.78 (0.52)2.50 (0.67)
All markers (NMPM)SI epithelium1.49 (0.09)1.19 (0.06)1.16* (0.08)1.13* (0.13)1.15* (0.09)
SI tumour2.40 (0.12)2.32 (0.25)3.24 (0.26)1.73 (0.21)1.47* (0.39)
  • Values represent mean (SEM).

  • *p<0.05, †p<0.01.

  • 5-ASA, 5-aminosalicylic acid; NMPM, number of mutations per marker; SI, small intestinal; TQ, thymoquinone.