Comparison of demographic and pre-RFA characteristics for all patients undergoing endoscopic therapy for BE-related neoplasia between 2008–2010 and 2011–2013
| 2008–2010 | 2011–2013 | p Value | |
|---|---|---|---|
| No of patients completing treatment protocol | 266 | 242 | NS |
| Mean age (range) | 68 (40–87) | 69 (44–90) | NS |
| M:F (%) | 80:20 | 84:16 | NS |
| Baseline histology, n (%) | NS | ||
| LGD | 7 (3%) | 7 (3%) | |
| HGD | 197 (74%) | 172 (71%) | |
| IMC | 62 (23%) | 63 (26%) | |
| Previous photodynamic therapy (%) | 9 | 3 | 0.02 |
| Baseline BE length at start of RFA (maximum extent), cm | 6 (1–20) | 4.7 (1–16) | NS |
| EMR prior to RFA, n (%) | 128 (48%) | 143 (60%) | 0.016 |
| Rescue EMR during RFA treatment, n (%) | 35 (13%) | 4 (2%) | <0.0001 |
| Mean time to end of protocol (months) | 12.6 | 10.3 | NS |
| Mean no of RFA treatments during treatment protocol | 2.6 (1–5) | 2.5 (1–5) | NS |
BE, Barrett's oesophagus; EMR, endoscopic mucosal resection; HGD, high-grade dysplasia; IMC, intramucosal cancer; LGD, low-grade dysplasia; NS, not statistically significant; RFA, radiofrequency ablation.