Lactate and alanine concentrations and lactate dehydrogenase activities measured in the pancreas of the different mouse strains used in this study that do not develop disease
| Tissues | Alanine (μmol/g of wet tissue) | Lactate (μmol/g of wet tissue) | Lactate dehydrogenase activity (mU/mg of protein) (n=3) |
|---|---|---|---|
| Wt (C57BL/6) (n=5) | 3.81±0.46† (*) | 3.00±0.31† (*) | 204.35±53.10 |
| p48Cre/+ (n=4) | 1.30±0.42 | 1.07±0.34 | 369.6±80.2 |
| LSL-KrasG12D/+ (n=4) | 1.16±0.28 | 1.12±0.26 | 229.88±20.50 |
| Pdx-1-Cre (PC) (n=6) | 0.93±0.06 | 0.95±0.13 | 222.54±55.93 |
Mean±SEM.
*p<0.05.
†Significantly higher compared with PC.
n, number of animals; wt, wild-type.