Socio-demographic and clinical features of patients with Barrett's oesophagus (BE) diagnosed with oesophageal adenocarcinoma (EAC) stratified based on the indication of the EAC diagnosing endoscopy
| EAC diagnosed by surveillance endoscopy (n=209) n (%) | EAC diagnosed by non-surveillance endoscopy (n=215) n (%) | p Value | |
|---|---|---|---|
| Male (%) | 208 (99.5) | 215 (100.0) | 0.49 |
| Race | 0.37 | ||
| White | 182 (87.1) | 178 (82.8) | |
| Black | 4 (1.9) | 8 (3.7) | |
| Other | 23 (11.0) | 29 (13.5) | |
| Age at BE diagnosis in years, mean (SD) | 60.6 (9.6) | 63.3 (10.0) | 0.01 |
| Age at EAC diagnosis in years, mean (SD) | 66.0 (9.1) | 67.9 (9.4) | 0.04 |
| Year of EAC diagnosis | 0.41 | ||
| 2004–2006 | 63 (30.1) | 56 (26.1) | |
| 2007–2009 | 86 (41.2) | 102 (47.4) | |
| 2010–2011 | 60 (28.7) | 57 (26.5) | |
| Number of endoscopies between BE diagnosis and EAC diagnosis, mean (SD) | 4.1 (3.6) | 3.8 (4.4) | 0.34 |
| Number of VA visits between BE and EAC diagnosis (quartile in BE cohort) | 0.31 | ||
| 1st quartile (8–36) | 18 (8.6) | 21 (9.8) | |
| 2nd quartile (37–68) | 27 (12.9) | 41 (19.0) | |
| 3rd quartile (69–125) | 62 (29.7) | 61 (28.4) | |
| 4th quartile (126–720) | 102 (48.8) | 92 (42.8) | |
| GI visit in the 1st year after BE index date | 103 (49.3) | 124 (57.7) | 0.08 |
| Presence of GORD diagnosis | 206 (98.6) | 207 (96.3) | 0.14 |
| PPI use (between BE and EAC diagnosis) | 192 (91.9) | 182 (84.7) | 0.02 |
| Propensity score to receive any endoscopy after BE diagnosis | 0.05 | ||
| 1st quartile (0.06–0.28) | 19 (9.1) | 28 (13.0) | |
| 2nd quartile (0.29–0.47) | 33 (15.8) | 49 (22.8) | |
| 3rd quartile (0.48–0.61) | 59 (28.2) | 63 (29.3) | |
| 4th quartile (0.62–0.87) | 98 (46.9) | 75 (34.9) | |
| Comorbidity score at BE diagnosis | 0.98 | ||
| 0 | 98 (46.9) | 103 (47.9) | |
| 1 | 61 (29.2) | 62 (28.8) | |
| 2+ | 50 (23.9) | 50 (23.3) | |
PPI, proton pump inhibitor; VA, Veteran Affairs.