| Sensitivity (95% CI) | Specificity (95% CI) | Positive LR (95% CI) | Negative LR (95% CI) | |
|---|---|---|---|---|
| Rome III criteria and normal Hb and CRP | 49.0% (34.8%–63.4%) | 89.2% (83.2%–93.6%) | 4.53 (2.67–7.64) | 0.57 (0.42–0.73) |
| Rome III criteria and HADS score ≥8 | 47.2% (35.3%–59.4%) | 89.1% (84.2%–92.9%) | 4.33 (2.76–6.76) | 0.59 (0.46–0.72) |
| Rome III criteria and high somatisation | 37.9% (26.2%–50.7%) | 94.8% (90.6%–97.5%) | 7.27 (3.74–14.2) | 0.66 (0.53–0.77) |
| Rome III criteria, normal Hb and CRP, and HADS score ≥8 | 34.0% (20.9%–49.3%) | 93.2% (87.9%–96.7%) | 5.04 (2.48–10.2) | 0.71 (0.55–0.84) |
| Rome III criteria, normal Hb and CRP, and high somatisation | 24.4% (12.4%–40.3%) | 96.8% (92.0%–99.1%) | 7.56 (2.63–21.7) | 0.78 (0.63–0.90) |
| Rome III criteria, no nocturnal passage of stool, and HADS score ≥8 | 22.2% (13.3%–33.6%) | 95.4% (91.7%–97.8%) | 4.84 (2.33–10.0) | 0.82 (0.70–0.91) |
| Rome III criteria, no nocturnal passage of stool, and high somatisation | 18.2% (9.8%–29.6%) | 99.0% (96.3%–99.9%) | 17.3 (4.45–67.6) | 0.83 (0.72–0.90) |