Metabolic pathways significantly differentially regulated in inflamed versus non-inflamed tissues
| Pathway | Direction | p Value |
|---|---|---|
| Dietary fibre binding | Repressed | 9.8×10−3 |
| Citric acid cycle | Repressed | 8.2×10−3 |
| Cytochrome metabolism | Repressed | 8.2×10−3 |
| Reactive oxygen species detoxification | Repressed | 7.5×10−4 |
| Bile acid synthesis | Repressed | 4.9×10−2 |
| Fatty acid oxidation | Repressed | 4.1×10−4 |
| Network size | Repressed | 4.0×10−2 |
| Steroid metabolism | Repressed | 4.0×10−2 |
| Pyrimidine catabolism | Induced | 4.0×10−2 |
| Nucleotide salvage pathway | Induced | 4.0×10−2 |
| Tryptophan metabolism | Induced | 4.0×10−2 |
| Propanoate metabolism | Repressed | 4.0×10−2 |
| Glycine, serine, alanine and threonine metabolism | Induced | 3.3×10−2 |
p Values were adjusted for multiple testing employing a false discovery rate-based method (Benjamini-Hochberg).