TableĀ 2

First cancers prospectively diagnosed by International Classification of Disease, ninth revision (ICD-9) diagnoses, groups of diagnoses and stratified on gender in Lynch syndrome (LS) patients without prior or prevalent cancer at first colonoscopy

GroupICD-9OrganFemalesMalesTotal
Colorectal cancers153Colon5972131
154Rectum/sigmoid101020
Endometrial and ovarian cancers182Endometrium7272
183Ovary1919
Upper GI cancers151Stomach358
152Duodenum336
156Biliary duct/gall bladder415
157Pancreas325
Urinary tract cancers188Urinary bladder44
189Kidney/ureter6713
Other LS or possibly LS cancers173*Skin*6612
174Breast1515
191Brain11
185Prostate66
Other cancers150Oesophagus11
159Abdominal unspecified11
160Nose11
161Larynx112
162Trachea11
170Osteosarcoma112
172Melanoma22
180Cervix11
186Testes11
193Thyroid11
194Neuroendocrine22
202Lymphoma11
204All/cll11
208Leukaemia unspecified11
Any cancer208127335
  • *Includes both epithelial skin cancer that is often not reported, and sebaceous gland invasive cancer. This specific diagnosis may not have been uniformly reported from the different centres.