|Released by necrotic cells|
|Monosodium urate||NACHT, LRR and PYD domains containing protein 3 (also known as cryopyrin; encoded by NLRP3, alias NALP3)|
|High-mobility group protein 1 (encoded by HMGB1)||
|Histone deacetylase complex subunit SAP130||C-type lectin domain family 4 member E (encoded by CLECSF9 also known as MINCLE)|
|IL-1α||IL-1R-1 and IL-1RAcP|
|IL-33||IL-1 receptor-like 1 (also known as protein ST2) and IL-1RAcP|
|S100 calcium-binding protein family|
|N-formylated peptides||Formyl peptide receptor|
|Products of extracellular matrix breakdown|
|Low-molecular weight fragments of hyaluronic acid||TLR4|
*Protein names used for DAMPs and receptors are official names provided by UniProtKB (http://www.uniprot.org); genes symbols are provided by Hugo Gene Nomenclature Committee (http://www.genenames.org).
DAMP, danger-associated molecular pattern; HSP, heat shock protein; IL, interleukin; IL-1R-1, IL-1 receptor type 1; IL-1RAcP, IL-1 receptor accessory protein; LRR, leucine-rich repeats; MINCLE, macrophage inducible C-type lectin; NACHT, NAIP, CIITA, HET-E and TP1; PYD, pyrin domain; TLR, toll-like receptor.