Reported triggers of acute-on-chronic liver failure, number (%)
| CANONIC n=303, (9) | Shi et al n=405, (14) | |
|---|---|---|
| Exacerbation hepatitis B | – | 145 (35.8) |
| Bacterial infection | 98 (32.6) | 113 (27.9) |
| GI haemorrhage | 40 (13.2) | 40 (9.8) |
| Active alcoholism within the past 3 months | 69 (24.5) | 25 (6.1) |
| Other (TIPSS, surgery, large volume paracentesis without albumin, hepatitis, alcoholic hepatitis) | 25 (8.6) | 9 (2) |
| Not identifiable | 126 (43.6) | 83 (20.4) |
| More than one | 39 (13.5) | 36 (8.9) |
CANONIC, EASL-CLIF Acute-on-Chronic Liver Failure in Cirrhosis; TIPSS, transjugular intrahepatic portosystemic shunt.