CD Patients with Vitamin B12 deficiency n=45 | CD Patients with normal Vitamin B12 levels n=112 | P value | |
---|---|---|---|
Age at diagnosis Median ( range) | 13 years (8–16 ) | 12 years ( 3–16 ) | n.s |
Male : Female | 1.8:1 | 2.1:1 | n.s |
Follow up period Median ( range) | 4 years (1–14 ) | 4 Years ( 1-14) | n.s |
Ileal involvement L1 and L3 | 36/45 (80%) | 85/112 ( 76%) | n.s |
Disease not in remission | 21/45 (47%) | 33/112 (30%) | <0.05 |
Patients on Azathioprine | 21/45 (47%) | 33/112 (30%) | n.s |
Patients on Methotrexate | 0/45 | 4/112 | n.s |
Patients on Anti TNF alfa treatment | Infliximab 20/45 (45%) Adalimumab 13/45 (29%) | Infliximab 54/112 (48%) Adalimumab 33/112 (29%) | n.s |
Patients with Ileal resection | 7/45 (16%) | 16/112 (14%) | n.s |