Description of the cohorts included in the analysis
| Cohort type | No. | Alcohol abuse | Age (range) | Male sex (%) |
| Initial GWAS cohort | ||||
| ACP cases (Pan-European Working Group) | 1959 | Yes | 50 (17–98) | 1674 (85.5%) |
| Controls (KORA, INCIPE) | 2637 | – | 49 (25–84) | 1073 (62.0%) |
| Controls (GESGA and KORA) | 1488 | Yes | 48 (26–74) | 1474 (99.1%) |
| Controls (KORA) | 1915 | No | 47 (25–74) | 686 (35.8%) |
| Replication cohort 1 | ||||
| NACP cases (Pan-European Working Group) | 584 | No | 21 (1–71) | 287 (49.1%) |
| Controls (LIFE) | 4892 | – | 63 (19–82) | 2379 (48.6%) |
| Replication cohort 2 | ||||
| NACP cases (France, Brest) | 546 | No | 18 (1–72) | 281 (51.5%) |
| Controls (France, Brest) | 1043* | – | 30 (17–75) | 295 (50.6%) |
| Replication cohort 3 | ||||
| NACP cases (Germany, Greifswald) | 520 | No | 41 (1–86) | 288 (55.4%) |
| Controls (Germany, Greifswald) | 760 | – | 32 (18–68) | 465 (61.0%) |
Further details of cohorts are provided in online supplementary table S1.
*In the French control cohort, age and gender data were available for 583 subjects only.
ACP, alcoholic chronic pancreatitis; GWAS, genome-wide association study; No., number of individuals after quality control filtering; NACP, non-alcohol-related chronic pancreatitis.