Patient characteristics
| Discovery cohort | Validation cohort | |||||
|---|---|---|---|---|---|---|
| Control | CD | UC | Control | CD | UC | |
| Patients, n (m/f) | 20 (10/10) | 15 (10/5) | 15 (7/8) | 19 (9/10) | 15 (10/5) | 15 (6/9) |
| Age, y* | 15.5 (11.6–16.6) | 13.9 (10.8–16.6) | 14.8 (13.3–16.3) | 15.3 (12.8–16.5) | 14.1 (10.8–15.6) | 13.7 (11.1–16.5) |
| PCDAI/PUCAI* | NA | 37.5 (32.5–57.5) | 45.0 (30.0–70.0) | NA | 47.5 (32.5–57.5) | 50.0 (40.0–70.0) |
| Classification | ||||||
| A1a | 3 | 2 | ||||
| A1b | 12 | 13 | ||||
| L1 | 3 | 0 | ||||
| L2 | 2 | 2 | ||||
| L3 | 10 | 13 | ||||
| L4a | 4 | 9 | ||||
| L4b | 1 | 2 | ||||
| B1 | 15 | 15 | ||||
| B2 | 0 | 0 | ||||
| P | 4 | 2 | ||||
| G0 | 12 | 13 | ||||
| G1 | 3 | 2 | ||||
| E1 | 0 | 0 | ||||
| E2 | 1 | 1 | ||||
| E3 | 1 | 1 | ||||
| E4 | 13 | 13 | ||||
| S0 | 10 | 10 | ||||
| S1 | 5 | 5 | ||||
*Values shown as median (IQR).
CD, Crohn's disease; NA, not applicable; PCDAI, Pediatric Crohn's Disease Activity Index; PUCAI, Pediatric UC Activity Index.