Table 2

Responsiveness of the gamma-glutamyl transpeptidase to platelet ratio (GPR), aspartate aminotransferase to platelet ratio Index (APRI) and fibrosis index based on four factors (FIB-4) during treatment of nucleoside/nucleotide analogues (NAs)

Spearman’s rp Value
ΔGPR* and Δscore †0.58p<0.001
ΔAPRI‡ and Δscore0.45p<0.001
ΔFIB-4§and Δscore0.39p<0.001

  • *Change in GPR between two liver biopsies during treatment of NAs.

  • †Change in METAVIR liver fibrosis score between two liver biopsies during treatment of NAs.

  • ‡Change in APRI between two liver biopsies during treatment of NAs.

  • §Change in FIB-4 between two liver biopsies during treatment of NAs.

  • APRI, aspartate aminotransferase to platelet ratio index; FIB-4, fibrosis index based on four factors; GPR, gamma-glutamyl transpeptidase to platelet ratio; NA, nucleoside/nucleotide analogue.