Table 3

Pharmacokinetic parameters (n=30)

PF-00547659
22.5 mg75 mg225 mg
AUC0-648 µg hour/mL558392011 100
Cmax µg/mL (median)2.0311.030.6

  • AUC0-648, area under the serum concentration–time curve from 0 to 248 hours; Cmax, maximum serum concentration.