Table 1

Comparison of taxa relative abundance in pre-PPI and post-PPI samples

Bacteria*Pre-PPI mean (SD)Post-PPI mean (SD)p Value
Phylum
Firmicutes70.70 (10.40)69.00 (10.40)0.5531
Bacteroidetes20.60 (12.30)24.00 (10.70)0.0914
Actinobacteria4.25 (4.76)2.35 (2.44)0.0059
Proteobacteria2.51 (2.96)3.01 (2.55)0.2296
Verrucomicrobia1.14 (4.22)1.10 (2.80)0.7726
Euryarchaeota0.65 (1.75)0.20 (0.54)0.3242
Tenericutes0.13 (0.44)0.22 (0.71)0.2708
Cyanobacteria0.02 (0.08)0.04 (0.11)0.4591
Family
Lachnospiraceae33.40 (20.50)28.60 (7.70)0.0059
Ruminococcaceae20.50 (9.35)21.30 (7.98)0.6373
Bacteroidaceae13.40 (10.70)14.90 (9.33)0.1961
Streptococcaceae1.49 (1.91)5.93 (5.30)0.0009
Prevotellaceae3.21 (8.23)4.09 (9.87)0.6814
Erysipelotrichaceae4.09 (3.30)2.74 (3.69)0.0132
Bifidobacteriaceae2.83 (4.39)1.39 (2.09)0.0275
Rikenellaceae1.61 (1.23)2.14 (1.90)0.0914
  • Bold values indicate statistical significance at p<0.05.

  • *Table includes only the eight most commonly identified phyla and families.

  • PPI, proton pump inhibitor.