Frozen samples from Europe (n=915)* | Fresh samples from Europe (n=96)† | Frozen samples from Africa (n=126)‡ | ||||
Point estimate | 95% CI | Point estimate | 95% CI | Point estimate | 95% CI | |
Sensitivity | 98.6% (412/418) | 96.9% to 99.5% | 98.0% (48/49) | 89.1% to 99.9% | 100% (114/114) | 96.8% to 100% |
Specificity | 100% (497/497) | 99.3% to 100% | 100% (47/47) | 92.5% to 100% | 100% (12/12) | 73.5% to 100% |
Positive likelihood ratio | N/A | N/A | N/A | N/A | N/A | N/A |
Negative likelihood ratio | 0.014 | 0.007 to 0.032 | 0.020 | 0.003 to 0.142 | 0.000 | N/A |
*Excluding four cases and six controls who did not give any result after two attempts.
†Excluding two cases and two controls who did not give any result after two attempts.
‡Excluding four cases who did not give any result after two attempts.