Faecal bile acid levels
| Mdr2−/− control (pmol/mg) | Mdr2−/− colesevelam (pmol/mg) | |
| αMCA | 21.4+/-11.6 | 399.8+/-34.2* |
| βMCA | 125.3+/-39.8 | 450+/-82.2* |
| οMCA | 334.4+/-192.3 | 300.1+/-59.1 |
| CA | 47.7+/-32.2 | 1141.9+/-371.9* |
| CDCA | 4.6+/-3.6 | 238.5+/-65.1* |
| DCA | 142.7+/-63.3 | 3072.7+/-914.8* |
| UDCA | 2.2+/-1.1 | 19.1+/-3.8* |
| LCA | 15.1+/-5.9 | 265.8+/-107.0* |
| TαMCA | 2.2+/-1.2 | 42.0+/-40.9* |
| TβMCA | 58.4+/-23.2 | 79.3+/-40.9 |
| TωMCA | 10.0+/-4.5 | 3.5+/-1.6* |
| TCA | 51.4+/-15.9 | 226.2+/-153.2 |
| TCDCA | 4.2+/-3.7 | 135.2+/-76.2* |
| TDCA | 0.8+/-0.8 | 49.4+/-40.9* |
| TUDCA | 0.8+/-0.6 | 3.3+/-1.7* |
| TLCA | nd | 3.5+/-2.2* |
| Total BAs | 839.9+/-280.3 | 6475.6+/-1202.6* |
*Significant difference from Mdr2−/−control; p<0.05.
BA, bile acid; CA, cholic acid; DCA, deoxycholic acid; MCA, mucholic acid; nd, not detectable; TCA, taurine-conjugated cholic acid; TCDCA, taurine-conjugated deoxycholic acid; TDCA, taurine-conjugated; deoxycholic acid; TCDCA, taurine-conjugated chenodeoxycholic acid; TLCA , taurine-conjugated lithocholic acid; TαMCA, tauro-alpha-muricholic acid; TβMCA, tauro-beta-muricholic acid; TωMCA, tauro-omega-muricholic acid; TUDCA, taurine-conjugated ursodeoxycholic acid.