cancer immunobiology

Cancer as microenvironmental, systemic and environmental diseases: opportunity for transdisciplinary microbiomics science
Kentaro Inamura, Tsuyoshi Hamada, Susan Bullman, Tomotaka Ugai, Shinichi Yachida, Shuji Ogino

Gut Oct 2022, 71 (10) 2107-2122; DOI: 10.1136/gutjnl-2022-327209
Autologous T cell responses to primary human colorectal cancer spheroids are enhanced by ectonucleotidase inhibition
Julie Bonnereau, Tristan Courau, Nicolas Asesio, Delphine Salfati, Fatiha Bouhidel, Hélène Corte, Sarah Hamoudi, Nassim Hammoudi, Julie Lavolé, Justine Vivier-Chicoteau, Victor Chardiny, Leon Maggiori, Mathieu Blery, Romain Remark, Cécile Bonnafous, Pierre Cattan, Antoine Toubert, Purnima Bhat, Matthieu Allez, Thomas Aparicio, Lionel Le Bourhis

Gut Apr 2023, 72 (4) 699-709; DOI: 10.1136/gutjnl-2021-326553
Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy
Jumin Huang, Di Liu, Yuwei Wang, Liang Liu, Jian Li, Jing Yuan, Zhihong Jiang, Zebo Jiang, WL Wendy Hsiao, Haizhou Liu, Imran Khan, Ying Xie, Jianlin Wu, Yajia Xie, Yizhong Zhang, Yu Fu, Junyi Liao, Wenjun Wang, Huanling Lai, Axi Shi, Jun Cai, Lianxiang Luo, Runze Li, Xiaojun Yao, Xingxing Fan, Qibiao Wu, Zhongqiu Liu, Peiyu Yan, Jingguang Lu, Mingrong Yang, Lin Wang, Yabing Cao, Hong Wei, Elaine Lai-Han Leung

Gut Apr 2022, 71 (4) 734-745; DOI: 10.1136/gutjnl-2020-321031
Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies
Paul Oster, Laurie Vaillant, Erika Riva, Brynn McMillan, Christina Begka, Caroline Truntzer, Corentin Richard, Marine M Leblond, Meriem Messaoudene, Elisavet Machremi, Emeric Limagne, Francois Ghiringhelli, Bertrand Routy, Gregory Verdeil, Dominique Velin

Gut Mar 2022, 71 (3) 457-466; DOI: 10.1136/gutjnl-2020-323392
Lactobacillus rhamnosus GG induces cGAS/STING- dependent type I interferon and improves response to immune checkpoint blockade
Wei Si, Hua Liang, Jason Bugno, Qi Xu, Xingchen Ding, Kaiting Yang, Yanbin Fu, Ralph R Weichselbaum, Xin Zhao, Liangliang Wang

Gut Mar 2022, 71 (3) 521-533; DOI: 10.1136/gutjnl-2020-323426
Targeting cancer-associated fibroblast-secreted WNT2 restores dendritic cell-mediated antitumour immunity
Tu-Xiong Huang, Xiang-Yu Tan, Hui-Si Huang, Yu-Ting Li, Bei-Lei Liu, Kai-Sheng Liu, Xinchun Chen, Zhe Chen, Xin-Yuan Guan, Chang Zou, Li Fu

Gut Feb 2022, 71 (2) 333-344; DOI: 10.1136/gutjnl-2020-322924
Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma
Robert C Grant, Robert Denroche, Gun Ho Jang, Klaudia M Nowak, Amy Zhang, Ayelet Borgida, Spring Holter, James T Topham, Julie Wilson, Anna Dodd, Raymond Jang, Rebecca Prince, Joanna M Karasinska, David F Schaeffer, Yifan Wang, George Zogopoulos, Scott Berry, Diane Simeone, Daniel J Renouf, Faiyaz Notta, Grainne O'Kane, Jennifer Knox, Sandra Fischer, Steven Gallinger

Gut Oct 2021, 70 (10) 1894-1903; DOI: 10.1136/gutjnl-2020-320730
Interleukin-1β-induced pancreatitis promotes pancreatic ductal adenocarcinoma via B lymphocyte–mediated immune suppression
Ryota Takahashi, Marina Macchini, Masaki Sunagawa, Zhengyu Jiang, Takayuki Tanaka, Giovanni Valenti, Bernhard W Renz, Ruth A White, Yoku Hayakawa, C Benedikt Westphalen, Yagnesh Tailor, Alina C Iuga, Tamas A Gonda, Jeanine Genkinger, Kenneth P Olive, Timothy C Wang

Gut Feb 2021, 70 (2) 330-341; DOI: 10.1136/gutjnl-2019-319912
Characterisation of innate lymphoid cell subsets infiltrating colorectal carcinoma
Paolo Carrega, Paola Orecchia, Linda Quatrini, Nicola Tumino, Roberta Venè, Roberto Benelli, Alessandro Poggi, Stefano Scabini, Maria Cristina Mingari, Lorenzo Moretta, Paola Vacca

Gut Dec 2020, 69 (12) 2261-2263; DOI: 10.1136/gutjnl-2020-320908
Targeting monocyte-intrinsic enhancer reprogramming improves immunotherapy efficacy in hepatocellular carcinoma
Man Liu, Jingying Zhou, Xiaoyu Liu, Yu Feng, Weiqin Yang, Feng Wu, Otto Ka-Wing Cheung, Hanyong Sun, Xuezhen Zeng, Wenshu Tang, Myth T S Mok, John Wong, Philip Chun Yeung, Paul Bo San Lai, Zhiwei Chen, Hongchuan Jin, Jie Chen, Stephen Lam Chan, Anthony W H Chan, Ka Fai To, Joseph J Y Sung, Minhu Chen, Alfred Sze-Lok Cheng

Gut Feb 2020, 69 (2) 365-379; DOI: 10.1136/gutjnl-2018-317257

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