gene regulation

Genetic and transcriptomic landscape of colonic diverticulosis
Jungkyun Seo, Hongwei Liu, Kristin Young, Xinruo Zhang, Temitope O Keku, Corbin D Jones, Kari E North, Robert S Sandler, Anne F Peery

Gut Mar 2024, gutjnl-2023-331267; DOI: 10.1136/gutjnl-2023-331267
Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer
Feda H Hamdan, Amro M Abdelrahman, Ana Patricia Kutschat, Xin Wang, Thomas L Ekstrom, Nidhi Jalan-Sakrikar, Catherine Wegner Wippel, Negar Taheri, Liezel Tamon, Waltraut Kopp, Joana Aggrey-Fynn, Aditya V Bhagwate, Roberto Alva-Ruiz, Isaac Lynch, Jennifer Yonkus, Robyn Laura Kosinsky, Jochen Gaedcke, Stephan A Hahn, Jens T Siveke, Rondell Graham, Zeynab Najafova, Elisabeth Hessmann, Mark J Truty, Steven A Johnsen

Gut Jun 2023, 72 (6) 1174-1185; DOI: 10.1136/gutjnl-2022-328154
Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment
Yibo Fan, Yuan Li, Xiaodan Yao, Jiangkang Jin, Ailing Scott, Bovey Liu, Shan Wang, Longfei Huo, Ying Wang, Ruiping Wang, Melissa Pool Pizzi, Lang Ma, Shan Shao, Matheus Sewastjanow-Silva, Rebecca Waters, Deyali Chatterjee, Bin Liu, Namita Shanbhag, Guang Peng, George Adrian Calin, Pawel Karol Mazur, Samir M Hanash, Jo Ishizawa, Yuki Hirata, Osamu Nagano, Zhenning Wang, Linghua Wang, Wa Xian, Frank McKeon, Jaffer A Ajani, Shumei Song

Gut Apr 2023, 72 (4) 624-637; DOI: 10.1136/gutjnl-2021-326581
Transcription factors as drivers of distinct pancreatic ductal adenocarcinoma (PDAC) programmes: a role for HNF4A
Giuseppe Riccardo Diaferia, Gioacchino Natoli

Gut May 2021, 70 (5) 816-817; DOI: 10.1136/gutjnl-2020-322814
Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis
Marina Barcena-Varela, Hannah Paish, Laura Alvarez, Iker Uriarte, Maria U Latasa, Eva Santamaria, Miriam Recalde, Maria Garate, Alex Claveria, Leticia Colyn, Maria Arechederra, Maria J Iraburu, Malgorzata Milkiewicz, Piotr Milkiewicz, Bruno Sangro, Stuart M Robinson, Jeremy French, Ana Pardo-Saganta, Julen Oyarzabal, Felipe Prosper, Krista Rombouts, Fiona Oakley, Jelena Mann, Carmen Berasain, Matias A Avila, Maite G Fernandez-Barrena

Gut Feb 2021, 70 (2) 388-400; DOI: 10.1136/gutjnl-2019-320205
YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition
Jaffer A Ajani, Yan Xu, Longfei Huo, Ruiping Wang, Yuan Li, Ying Wang, Melissa Pool Pizzi, Ailing Scott, Kazuto Harada, Lang Ma, Xiaodan Yao, Jiankang Jin, Wei Zhao, Xiaochuan Dong, Brian D Badgwell, Namita Shanbhag, Ghia Tatlonghari, Jeannelyn Santiano Estrella, Sinchita Roy-Chowdhuri, Makoto Kobayashi, Jody V Vykoukal, Samir M Hanash, George Adrian Calin, Guang Peng, Ju-Seog Lee, Randy L Johnson, Zhenning Wang, Linghua Wang, Shumei Song

Gut Jan 2021, 70 (1) 55-66; DOI: 10.1136/gutjnl-2019-319748
Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in oesophageal adenocarcinoma
Li Chen, Moli Huang, Jasmine Plummer, Jian Pan, Yan Yi Jiang, Qian Yang, Tiago Chedraoui Silva, Nicole Gull, Stephanie Chen, Ling Wen Ding, Omer An, Henry Yang, Yulan Cheng, Jonathan W Said, Ngan Doan, Winand NM Dinjens, Kevin M Waters, Richard Tuli, Simon A Gayther, Samuel J Klempner, Benjamin P Berman, Stephen J Meltzer, De-Chen Lin, H Phillip Koeffler

Gut Apr 2020, 69 (4) 630-640; DOI: 10.1136/gutjnl-2019-318325
Meta-analysis of genome-wide association studies and functional assays decipher susceptibility genes for gastric cancer in Chinese populations
Caiwang Yan, Meng Zhu, Yanbing Ding, Ming Yang, Mengyun Wang, Gang Li, Chuanli Ren, Tongtong Huang, Wenjun Yang, Bangshun He, Meilin Wang, Fei Yu, Jinchen Wang, Ruoxin Zhang, Tianpei Wang, Jing Ni, Jiaping Chen, Yue Jiang, Juncheng Dai, Erbao Zhang, Hongxia Ma, Yanong Wang, Dazhi Xu, Shukui Wang, Yun Chen, Zekuan Xu, Jianwei Zhou, Guozhong Ji, Zhaoming Wang, Zhengdong Zhang, Zhibin Hu, Qingyi Wei, Hongbing Shen, Guangfu Jin

Gut Apr 2020, 69 (4) 641-651; DOI: 10.1136/gutjnl-2019-318760
Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming
Marina Koutsioumpa, Maria Hatziapostolou, Christos Polytarchou, Ezequiel J Tolosa, Luciana L Almada, Swapna Mahurkar-Joshi, Jennifer Williams, Ana Belen Tirado-Rodriguez, Sara Huerta-Yepez, Dimitrios Karavias, Helen Kourea, George A Poultsides, Kevin Struhl, David W Dawson, Timothy R Donahue, Martín E Fernández-Zapico, Dimitrios Iliopoulos

Gut Jul 2019, 68 (7) 1271-1286; DOI: 10.1136/gutjnl-2017-315690
Comprehensive characterisation of compartment-specific long non-coding RNAs associated with pancreatic ductal adenocarcinoma
Luis Arnes, Zhaoqi Liu, Jiguang Wang, Carlo Maurer, Irina Sagalovskiy, Marta Sanchez-Martin, Nikhil Bommakanti, Diana C Garofalo, Dina A Balderes, Lori Sussel, Kenneth P Olive, Raul Rabadan

Gut Mar 2019, 68 (3) 499-511; DOI: 10.1136/gutjnl-2017-314353

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