Summary
Genetic polymorphism of the human parotid salivary acid phosphatase (s-AcP) in the Japanese population is described. The use of polyacrylamide gel isoelectric focusing electrophoresis with the pH range of 4.0–6.5 enabled us to discern three variant patterns controlled by two codominant alleles at the single autosomal locus. The two alleles were designated s-AcP: A and s-AcP:a, and the gene frequencies calculated from 183 Japanese subjects were s-AcP:A=0.2268±0.022, s-AcP:a=0.7732±0.022, respectively. The distribution of phenotypes fitted the Hardy-Weinberg equilibrium.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Azen EA (1977) Salivary peroxidase (SAPX): Genetic modification and relationship to the proline-rich (Pr) and acidic (Pa) proteins. Biochem Genet 15:9–29
Merritt AD, Rivas ML, Bixler D, Newell R (1973) Salivary and pancreatic amylase: Electrophoretic characterizations and genetic studies. Am J Hum Genet 25:510–522
Tan SG (1976) Human saliva esterase: Genetic studies. Hum Hered 26:207–216
Tan SG, Ashton GC (1976a) Saliva acid phosphatases: Genetic studies. Hum Hered 26:81–89
Tan SG, Ashton GC (1976b) An autosomal glucose-6-phosphate dehydrogenase (hexose-6-phosphate dehydrogenase) polymorphism in human saliva. Hum Hered 26:113–123
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ikemoto, S., Hinohara, H., Tsuchida, S. et al. Phenotype and gene frequencies of acid phosphatase (s-AcP) in the human parotid saliva. Hum Genet 71, 30–32 (1985). https://doi.org/10.1007/BF00295663
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00295663