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Comparison of effects of ingested mediumand long-chain triglyceride on gallbladder volume and release of cholecystokinin and other gut peptides

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Abstract

In a double-blind, crossover study of the effect of ingested medium-chain triglyceride (MCT) and long-chain triglyceride (LCT) in six normal subjects, the gallbladder did not contract after ingestion of MCT but instead had significantly increased in volume at 2 hr after the meal. Plasma cholecystokinin (CCK) increased after the MCT meal, but gastrin, motilin, pancreatic polypeptide (PP), and GIP were unaffected. The long-chain triglyceride meal evoked a brisk and sustained gallbladder contraction, higher levels of CCK, and a significant increase in plasma PP and GIP levels.

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Isaacs, P.E.T., Ladas, S., Forgacs, I.C. et al. Comparison of effects of ingested mediumand long-chain triglyceride on gallbladder volume and release of cholecystokinin and other gut peptides. Digest Dis Sci 32, 481–486 (1987). https://doi.org/10.1007/BF01296030

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  • DOI: https://doi.org/10.1007/BF01296030

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