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Fulminant hepatic failure in nonmetastatic renal cell carcinoma

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Summary

Paraneoplastic manifestations including reversible abnormal serum liver biochemistry are known to occur in at least one third of patients with renal cell carcinoma. This hepatic dysfunction has always been regarded as benign in nature and attributed to reactive nonspecific hepatitis. In contrast to this belief, we report here a more devastating course of an asymptomatic patient with nonmetastatic renal cell carcinoma which ranged from mere serum liver biochemistry derangement to a fatal end with fulminant hepatic failure within 10 days. To our knowledge, this is the first report of such a case.

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Authors and Affiliations

  1. Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong

    Jane W. S. Fang MB, MRCP, Johnson Y. N. Lau MB, MRCP, P. C. Wu MD, FRcPath, FRCPA &  C. L. Lai MB, FRCP, FRCP(E)

Authors
  1. Jane W. S. Fang MB, MRCP
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  2. Johnson Y. N. Lau MB, MRCP
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  3. P. C. Wu MD, FRcPath, FRCPA
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  4. C. L. Lai MB, FRCP, FRCP(E)
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Fang, J.W.S., Lau, J.Y.N., Wu, P.C. et al. Fulminant hepatic failure in nonmetastatic renal cell carcinoma. Digest Dis Sci 37, 474–477 (1992). https://doi.org/10.1007/BF01307746

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  • DOI: https://doi.org/10.1007/BF01307746

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