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Postoperative and long-term results of ileal pouch-anal anastomosis for ulcerative colitis and familial polyposis coli

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Abstract

The immediate postoperative and long-term functional results of 51 ulcerative colitis patients and 21 familial polyposis patients who underwent ileal J-pouch-anal anastomosis were compared in this study. The incidence of postoperative complications requiring reoperation was not statistically different in both groups. The mean daily stool frequency was significantly higher in colitis patients. Pouchitis occurred in 44% of colitis patients but not in polyposis patients (P<0.005). Symptoms of pouchitis included bloody diarrhea, urgency, abdominal pain, weight loss, fever, and arthritis. Six colitis patients required pouch excision because of intractable pouchitis. The overall pouch excision rate was 22% in ulcerative colitis patients and 5% in familial polyposis patients. Patient satisfaction was good in 46% of ulcerative colitis patients and 76% of polyposis patients (P<0.05). Our data demonstrate that the long-term outcome of ileal pouch-anal anastomosis is more favorable in polyposis patients than in colitis patients. Pouchitis is a major long-term complication occurring exclusively in colitis patients.

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Authors and Affiliations

  1. Department of Gastrointestinal and Liver Diseases, University Hospital Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands

    J. M. J. I. Salemans MD, F. M. Nagengast PhD, E. J. C. Lubbers PhD & J. H. Kuijpers PhD

  2. Department of Surgery, University Hospital Nijmegen, Nijmegen, The Netherlands

    J. M. J. I. Salemans MD, F. M. Nagengast PhD, E. J. C. Lubbers PhD & J. H. Kuijpers PhD

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  1. J. M. J. I. Salemans MD
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  2. F. M. Nagengast PhD
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  3. E. J. C. Lubbers PhD
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  4. J. H. Kuijpers PhD
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Salemans, J.M.J.I., Nagengast, F.M., Lubbers, E.J.C. et al. Postoperative and long-term results of ileal pouch-anal anastomosis for ulcerative colitis and familial polyposis coli. Digest Dis Sci 37, 1882–1889 (1992). https://doi.org/10.1007/BF01308083

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  • DOI: https://doi.org/10.1007/BF01308083

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