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Chest pain and dysphagia in patients with prolonged peristaltic contractile duration of the esophagus

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Abstract

Dysphagia and chest pain are well-described symptoms in subjects with achalasia, diffuse esophageal spasm (DES), and high-amplitude peristaltic contractions, a subset of nonspecific motor disorders (NEMD). We observed a high incidence of chest pain and dysphagia in a different NEMD subgroup characterized by prolonged peristaltic contractile duration (PPCD) and normal contractile amplitude. We compared the manometric characteristics of patients with PPCD to healthy controls and compared the clinical profile of PPCD patients to that of patients with achalasia, DES, and high-amplitude peristalsis. In 2o patients with PPCD, mean contractile duration was 7.4±0.3 sec, significantly greater than healthy controls (3.7±0.1 sec) (P<0.001). PPCD was associated with an 85% incidence of chest pain and 65% incidence of dysphagia. These symptoms were similar to those observed in patients with achalasia, DES, and highamplitude peristalsis. In PPCD patients, chest pain was more frequently of long duration in comparison to achalasia and DES. PPCD was encountered more frequently than either achalasia or DES in patients referred to our laboratory. This study suggests that in symptomatic NEMD patients, abnormal duration of peristaltic contractions, rather than abnormal amplitude, may be a distinguishing manometric feature.

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References

  1. Benjamin SB, Gerhardt DC, Castell DO: High amplitude peristaltic esophageal contractions associated with chest pain and/or dysphagia. Gastroenterology 77:478–483, 1979

    Google Scholar 

  2. Pope CE: Motor disorders of the esophagus. Postgrad Med 61:118–125, 1977

    Google Scholar 

  3. Herrington JP, Burns TW, Balart LA: Chest pain, dysphagia, high amplitude esophageal peristalsis: A clinical and manometric study. South Med J 76:599–602, 1983

    Google Scholar 

  4. Castell DO: Achalasia and diffuse esophageal spasm. Arch Intern Med 136:571–579, 1976

    Google Scholar 

  5. Castell DO: The spectrum of esophageal motility disorders. Gastroenterology 76:639–640, 1979

    Google Scholar 

  6. Arndorfer RC, Stef JJ, Dodds WJ, Linehan JH, Hogan WJ: Improved infusion system for intraluminal esophageal manometry. Gastroenterology 73:23–27, 1977

    Google Scholar 

  7. Dodds WJ: Instrumentation and methods for intraluminal esophageal manometry. Arch Intern Med 136:515–523, 1976

    Google Scholar 

  8. Colton, T.: Statistics in Medicine. Boston, Little, Brown, 1974, p 38

    Google Scholar 

  9. Castell DO, Knuff TE, Brown FC, Gerhardt DC, Burns TW, Gaskins RD: Clinical Conference: Dysphagia. Gastroenterology 76:1015–1024, 1979

    Google Scholar 

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This study was supported solely by a grant from the Alton Ochsner Medical Foundation.

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Herrington, J.P., Burns, T.W. & Balart, L.A. Chest pain and dysphagia in patients with prolonged peristaltic contractile duration of the esophagus. Digest Dis Sci 29, 134–140 (1984). https://doi.org/10.1007/BF01317054

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  • DOI: https://doi.org/10.1007/BF01317054

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