Abstract
To determine the possible factors that may contribute to the development of peptic stricture of the esophagus, clinical and manometric features were compared in patients with symptomatic gastroesophageal reflux and those with peptic strictures of the esophagus. Patients with stricture were older and had a longer duration of heartburn than patients without a stricture. Most importantly, patients with stricture had a more marked decrease in lower esophageal sphincter (LES) pressure, 4.9±0.5 mm Hg, than patients without a stricture, 7.5±0.6 mm Hg, P<0.01. The LES pressure in all patients with stricture was below 8 mm Hg, and did not overlap with normal values. Patients with stricture had either a nonspecific motor abnormality or aperistalsis (64%), compared to patients with symptomatic reflux (32%), P<0.05. Thus, peptic stricture of the esophagus is commonly associated with a long duration of reflux symptoms in patients with a very low LES pressure and esophageal motor disorder.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Creamer B, Donoghue E, Code CF: Pattern of esophageal motility in diffuse spasm. Gastroenterology 34:782–796, 1958
Palmer ED: Subacute erosive (“peptic”) esophagitis: Clinical study of one hundred cases. Arch Intern Med 94:364–374, 1954
Cohen S, Harris LD: Does hiatus hernia affect competence of the gastroesophageal sphincter? N Engl J Med 284:1053–1056, 1971
Haddad J: Relation of gastroesophageal reflux to yield sphincter pressures. Gastroenterology 58:175–184, 1970
Cohen S, Harris LD: Lower esophageal sphincter pressure as an index of lower esophageal spincter strength. Gastroenterology 58:157–162, 1970
Pope CE, II: Is LES enough? Gastroenterology 71:328–329, 1976
Fisher RS, Malmud LS, Roberts GS, Lobis IF: The lower esophageal sphincter as a barrier to gastroesophageal reflux. Gastroenterology 72:19–22, 1977
Heitman P, Csendes A, Strauszer T: Esophageal strictures and lower esophagus lined with columnar epithelium. Functional and morphologic studies. Am J Dig Dis 16:307–319, 1971
Larrain A, Csendes A, Uribe P, Ayala M: Manometric evaluation after posterior gastropexy for treatment of strictures of the esophagus secondary to reflux. Surg Gynecol Obstet 136:564–566, 1973
Larrain A, Csendes A, Pope CE, II: Surgical correction of reflux. An effective therapy for esophageal strictures. Gastroenterology 69:578–583, 1975
Naef AP, Savary M: Conservative operations for peptic esophagitis with stenosis in columnar-lined lower esophagus. Ann Thorac Surg 13:543–551, 1972
Stanciu C, Bennett JR: Oesophageal acid clearing: One factor in the production of reflux esophagitis. Gut 15:852–857, 1974
DeMeester TR, Johnson LF, Guy JJ, Toscano MS, Hall AW, Skinner DB: Patterns of gastroesophageal reflux in health and disease. Ann Surg 184:459–470, 1976
Johnson LF, DeMeester TR, Haggitt RC: Esophageal epithelial response to gastroesophageal reflux. A quantitative study. Am J Dig Dis 23:498–509, 1978
Cohen S, Fisher RS, Lipshutz WH, Turner R, Myers A, Schumacher R: The pathogenesis of esophageal dysfunction in scleroderma and Raynaud's disease. J Clin Invest 51:2663–2668, 1972
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ahtaridis, G., Snape, W.J. & Cohen, S. Clinical and manometric findings in benign peptic strictures of the esophagus. Digest Dis Sci 24, 858–861 (1979). https://doi.org/10.1007/BF01324902
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01324902