ArticleNutrient ingestion increases rectal sensitivity in humans
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Lipid-Induced Colonic Hypersensitivity in the Irritable Bowel Syndrome: The Role of Bowel Habit, Sex, and Psychologic Factors
2007, Clinical Gastroenterology and HepatologyDo we need to perform rectal distention tests to diagnose IBS in clinical practice?
2002, GastroenterologyAlterations in cerebral potentials evoked by rectal distension in irritable bowel syndrome
2001, American Journal of GastroenterologyCitation Excerpt :Therefore, we hypothesized that this technique may provide further objective evidence of alterations in intestinal afferent pathways in patients with IBS. Evaluation in the postprandial state is of particular interest, considering that, in addition to altering colonic motor activity (10), nutrient ingestion has been reported to enhance rectal sensitivity (11), and to alter colonic tone (12), as well as provoking dysmotility in IBS patients (13). Our specific aims were to study patients with IBS and age-matched healthy controls and 1) compare the characteristics of mechanically-evoked rectal cerebral potentials; and 2) determine if any differences in such evoked potentials in IBS patients are more prominent in the postprandial state.
Answers to the questions (with references)
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