Cell
Volume 55, Issue 4, 18 November 1988, Pages 627-635
ArticleActivation of c-myc by woodchuck hepatitis virus insertion in hepatocellular carcinoma
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Cited by (179)
Molecular biology of hepatitis B virus infection
2015, VirologyCitation Excerpt :What these are remains unknown. In a small fraction of woodchuck HCCs, proximal integration of WHV DNA along with transcriptional activation may be found instead at N-myc1 or C-myc (Fourel et al., 1990; Hsu et al., 1988). To address issues related to the oncogenicity of C-myc and N-myc2, Buendia and colleagues made transgenic mice containing either WHV/Nmyc2 or WHV/Cmyc DNA fragments cloned from woodchuck HCCs (Renard et al., 2000; Terradillos et al., 1997).
Chapter 8 - The Laboratory Woodchuck (Marmota monax)
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