Cell
Volume 79, Issue 5, 2 December 1994, Pages 791-803
ArticleOverexpression of cadherins and underexpression of β-catenin inhibit dorsal mesoderm induction in early Xenopus embryos
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Cited by (604)
Mitochondrial leak metabolism induces the Spemann-Mangold Organizer via Hif-1α in Xenopus
2023, Developmental CellEs-β-CATENIN affects the hemolymph-testes barrier in Eriocheir sinensis by disrupting cell junctions and cytoskeleton
2023, International Journal of Biological MacromoleculesMink1 regulates spemann organizer cell fate in the xenopus gastrula via Hmga2
2023, Developmental BiologyThe organizer: What it meant, and still means, to developmental biology
2023, Current Topics in Developmental BiologyThe role of Wnt signaling in Xenopus neural induction
2023, Current Topics in Developmental BiologyUncovering the mesendoderm gene regulatory network through multi-omic data integration
2022, Cell ReportsCitation Excerpt :Alternatively, these enhancers could be similarly regulated in dorsal and ventral regions of the embryo by Sia1 or Ventx2, but other spatial-specific factors could change the topology of the chromatin to target two distinct sets of genes from the same enhancer. Second, we identified this same pattern in other dorsal-ventral pairs of TFs, such as the signaling pathway TF Ctnnb1 (Wnt signaling TF) (Stevens et al., 2017; Heasman et al., 1994), Foxh1 (Nodal signaling co-factor) (Chen et al., 1996), and Smad1 (BMP signaling TF) (Graff et al., 1996). The first two are both important for establishing the dorsal domain of the embryo, while Smad1 helps establish ventral identity.
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