HLA-DR and -DQ genotypes of celiac disease patients serologically typed to be non-DR3 or non-DR5/7
References (23)
- et al.
Susceptibility to develop celiac disease is primarily associated with HLA-DQ alleles
Hum Immunol
(1990) - et al.
A radioimmunoassay typing study of non-DQw2-associated celiac disease
Clin Immunol Immunopathol
(1986) - et al.
The distribution of HLA class II alleles among Norwegian Caucasians
Hum Immunol
(1990) - et al.
HLA-DP typing by DNA amplification and hybridization with allele-specific oligonucleotides
Hum Immunol
(1989) - et al.
Celiac disease
- et al.
Evidence for a primary association of celiac disease to a particular HLA-DQ α/ß heterodimer
J Exp Med
(1989) - et al.
T lymphocyte recognition of a celiac disease-associated cis- or trans-encoded HLA-DQ α/ß heterodimer
J Immunol
(1990) - et al.
HLA-DR3 and DR7-negative celiac disease
- et al.
Genetic markers in Australian Caucasian subjects with coeliac disease
Tissue Antigens
(1987) - et al.
HLA-DQß gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
Nature
(1987)
Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility
Cited by (110)
The HLA complex and coeliac disease
2021, International Review of Cell and Molecular BiologyProfiling Celiac Disease-Related Transcriptional Changes
2018, International Review of Cell and Molecular BiologyCeliac Disease, the Microbiome, and Probiotics
2017, The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics, and DysbiosisHuman leukocyte antigen (HLA) DQ2/DQ8 prevalence in recurrent pregnancy loss women
2016, Autoimmunity ReviewsCitation Excerpt :It is now accepted that the alleles encoding HLA-DQ2, specifically, HLA-DQ2.5 (DQA1*05 and DQB1*02) are expressed in around 90% of CD patients. Most of the remaining patients (without HLA-DQ2.5) carry the alleles encoding HLA-DQ8 molecules (DQA1*03 and DQB1*03:02 alleles) [50-52]. In almost all CD patients who carry neither HLA-DQ2.5 nor HLA-DQ8, one of the two alleles encoding HLA-DQ2.5 is present: most commonly DQB1*02 (HLA-DQ2.2) and in a minority of cases, DQA1*05 (HLADQ7.5) [51].
The genetics of celiac disease: A comprehensive review of clinical implications
2015, Journal of AutoimmunityCitation Excerpt :This is conditioned to the presence of at least one copy of the HLA-DQA1*05 allele. Most of the remaining patients (without HLA-DQ2.5) carry the DQA1*03 and DQB1*03:02 alleles, which encode the HLA-DQ8 molecule [29]. A gene dosage effect for HLA-DQ8 has been also proposed [30].