Histidinemia in mice: A metabolic defect treated using a novel approach to hepatocellular transplantation☆
References (59)
- et al.
Biochemical investigation of histidinemia in schizophrenic patients
Biol Psychiatry
(1990) - et al.
The nutritional therapy of histidinemia
J Pediatr
(1979) - et al.
Identification of the mutation in murine histidinemia (his) and genetic mapping of the murine histidase locus (Hal) on chromosome 10
Genomics
(1993) - et al.
Cloning and expression of rat histidase
- et al.
Treatment of enzyme deficiency by hepatocyte transplantation in rats
J Surg Res
(1985) - et al.
Human liver cell transplantation
- et al.
Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits
J Biol Chem
(1992) - et al.
Hepatocellular transplantation into the lung for temporary support of acute liver failure in the rat
Gastroenterology
(1992) - et al.
Cell contact but not junctional communication (dye coupling) with biliary epithelial cells is required for hepatocytes to maintain differentiated functions
Exp Cell Res
(1987) Disorders of histidine metabolism
Histidinemia: a biochemical variant or a disease?
J Am Coll Nutr
Speech and histidinemia: methodology and evaluation of four cases
Dev Med Child Neurol
A familial disturbance of histidine metabolism
N Engl J Med
Histidinaemia in mouse and man
Arch Dis Child
Assignment of histidaseregulating locus to chromosome 10 of the mouse
Biochem Genet
The biochemistry and genetics of histidinaemia in the mouse
Reversal of ischemic liver failure by intrasplenic liver cell transplantation
J Pediatr Surg
Intrasplenic hepatocyte transplantation in rats with experimental liver injury: morphological and morphometric studies
J Pathol
The pulmonary vascular bed as a site for implantation of isolated liver cells in inbred rats
Transplantation
Hepatocyte transplantation into the lung for treatment of acute hepatic failure in the rat
Transplant Proc
Transplantation of isolated hepatocytes into the pancreas
Eur Surg Res
Hepatocyte transplantation
Intraperitoneal hepatocyte transplantation: morphological results
Virchows Arch A Pathol Anat Histopathol
Restoration of liver function in Gunn rats without immunosuppression using transplanted microencapsulated hepatocytes
Hepatology
Evidence of metabolic activity of adult and fetal rat hepatocytes transplanted into solid supports
Transplantation
Intraperitoneal hepatocyte transplantation: morphologic findings and clinical relevance
Helv Chir Acta
Hepatocyte transplantation into spleen or solid supports: comparison of morphology, function, and proliferative response
Transplant Proc
High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study
J Cell Biol
Hepatocyte transplantation for enzyme deficiency disease in congenic rats
Transplantation
Cited by (42)
Kupffer cell transplantation in mice for elucidating monocyte/macrophage biology and for potential in cell or gene therapy
2016, American Journal of PathologyCitation Excerpt :We noted the ability of transplanted KC to express pro- and anti-inflammatory cytokines in a context-specific manner (ie, after lipopolysaccharide or liver injury25), implying that transplanted KC flexibly adopted either pro- or anti-inflammatory phenotypes as was needed. Previously, when NPC, including KC, were cotransplanted with hepatocytes in the peritoneal cavity, transplanted hepatocytes showed superior survival.56 Therefore, cotransplantation of these cell types might be worth considering in applications of hepatocyte transplantation.
Increased sensitivity of histidinemic mice to UVB radiation suggests a crucial role of endogenous urocanic acid in photoprotection
2011, Journal of Investigative DermatologyCitation Excerpt :These mutations lead to an increased concentration of histidine and a decreased concentration of UCA in blood, urine, and epidermis (Baden et al., 1969; Lam et al., 1996). A spontaneous mutation (R322Q) in the Hal gene leading to the loss of histidase activity was detected in histidinemic mice, also known as Peruvian mice (Kacser et al., 1973; Selden et al., 1995). To the best of our knowledge, the sensitivity of histidinemic mice to UV-induced DNA damage has not been reported so far.
Barriers to the successful treatment of liver disease by hepatocyte transplantation
2010, Journal of HepatologyIs the filaggrin-histidine-urocanic acid pathway essential for stratum corneum acidification
2010, Journal of Investigative DermatologyTissue Engineering of Organ Systems
2008, Tissue EngineeringCellular Transplants for Liver Diseases
2007, Cellular Transplantation
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Supported by Action Research, London, England, and the Hammersmith and Queen Charlottes Special Health Authority, London, England.