Original articleHepatitis C viral quasispecies in hepatitis C virus carriers with normal liver enzymes and patients with type C chronic liver disease☆
References (31)
- et al.
The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance-a review
Gene
(1985) - et al.
Hypervariable regions in the putative glycoprotein of hepatitis C virus
Biochem Biophys Res Commun
(1991) - et al.
Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins
Virology
(1991) - et al.
Marked sequence diversity in the putative envelope proteins of hepatitis C viruses
Virus Res
(1992) - et al.
Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
Genomics
(1989) - et al.
Hepatitis C viral complexity through single strand conformation polymorphism in association with response to interferon therapy
Gastroenterology
(1995) Variability of HIV infections
J Theor Biol
(1992)- et al.
Quantitative analysis of hepatitis C virus RNA in serum during interferon alfa therapy
Gastroenterology
(1993) - et al.
Long-term mortality after transfusion-associated non-A, non-B hepatitis
N Engl J Med
(1992) - et al.
Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus
Hepatology
(1990)
Quantitation of hepatitis C virus RNA in serum of asymptomatic blood donors and patients with type C chronic liver disease
Hepatology
(1993)
Serum hepatitis C virus RNA quantity and histological features of hepatitis C virus carriers with persistently normal alanine aminotransferase levels
Hepatology
(1994)
Rapid evolution of RNA viruses
Ann Rev Microbiol
(1987)
Implication of a quasispecies genome structure: effect of frequent, naturally occurring amino acid substitutions on the antigenicity of foot-and-mouth disease virus
Structural and serological evidence for a novel mechanism of antigenic variation in foot-and-mouth disease virus
Nature
(1990)
Cited by (65)
The quasispecies nature and biological implications of the hepatitis C virus
2009, Infection, Genetics and EvolutionCompartmentalization of hepatitis C viral quasispecies
2003, Frontiers in Viral HepatitisHepatitis C virus quasispecies: Misunderstood and mistreated?
2003, Liver TransplantationHepatitis C virus genetic variability: Pathogenic and clinical implications
2003, Clinics in Liver DiseaseEvolution of hepatitis C viral quasispecies after liver transplantation
2002, GastroenterologyCitation Excerpt :We calculated this diversity in two ways. First, we determined the average nucleotide distance of all distances generated by pairwise comparison of all 10 sequences (45 distances).27 Then we calculated the average number of nucleotide differences between every sequenced clone of each sample and their respective consensus sequence.28
Real-time RT-PCR for quantitation of hepatitis C virus RNA
2002, Journal of Virological Methods
- ☆
Supported by a grant-in-aid from the Ministry of Education, Science, and Culture of Japan and the Research Group of Intractable Hepatitis, sponsored by the Ministry of Health and Welfare of Japan.
Copyright © 1995 Published by Elsevier Inc.