New Techniques in Colon Imaging Tuesday, May 21, 2002

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**464 Early detection of colorectal adenoma and early cancer. Benefit of chromo-, magnification- or conventional colonoscopy? A multicenter prospective trial

Ralf Kiesslich, Carla Ohlerth, Harold Graebner, Mirko Machate, Biju J. Thanka Nadar, Martin Hahn, Günther Herrmann, Heinz H. Koehler, Markus Neurath, Peter R. Galle, Michael Jung, Mainz, Germany; Ludwigsburg, Germany

Introduction: Chromoendoscopy facilitates the diagnosis of epithelial changes. The pit pattern (PP) classification in combination with newly developed endoscopes may allow a differention of adenomatous and nonadenomatous lesions. Aim of the present study was the evaluation of

**465 Chromoendoscopy as a novel method for the detection of colitis-associated dysplasias and colon carcinoma in ulcerative colitis: Results of a prospective randomised trial

Ralf Kiesslich, Johannes Fritsch, Martin Holtmann, Heinz H. Koehler, Manfred Stolte, Michael Jung, Peter R. Galle, Markus Neurath, Mainz, Germany; Bayreuth, Germany

Introduction: Ulcerative colitis (UC) is associated with the risk for developing colitis-associated dysplasias (CAD) and colon carcinoma (CAC). We hypothesized that chromoendoscopy (CE) with methylene blue (MB) would facilitate early detection of CAC in long-lasting UC compared with conventional colonoscopy alone. Methods: Between

**466 Endoscopic assessment of colonic polyps without magnification: Is it good enough to distinguish adenomas from hyperplastic polyps?

Bjorn Rembacken, Leeds, UK

Background: Japanese endoscopists have devised a classification of mucosal crypt pattern that has been shown to be helpful when distinguishing between innocent hyperplastic polyps, adenomas, and invasive malignancies at colonoscopy. Aims: To determine whether adenomatous lesions can be accurately distinguished from non-neoplastic polyps by spraying with indigo carmine dye without the use of a magnifying colonoscope. Methods: The endoscopic appearance of all colonic

**467 CT colonography (virtual colonoscopy) compared with colonoscopy in 231 paired examinations

Regnar B. Arnesen, Sven Adamsen, Hans Otto Raaschou, Eric von Benzon, Ole Hart-Hansen, Hillerod, Denmark

Computed tomographic colonography (CTC) was evaluated as a method for detecting colorectal polyps and cancer, by using conventional colonoscopy (CC) as the standard of reference. Method: In a paired prospective blinded design, CTCs were performed immediately before same-day CCs. All findings were validated comparing CTCs with video-recordings of the CCs. Results: A total of 205 polyps and 5

**468 Patient preferences and satisfaction with virtual vs. conventional colonoscopy

Roshini Rajapaksa, Michael Macari, Elizabeth Weinshel, Edmund J. Bini, New York, NY

Purpose: To determine patient preferences and satisfaction with regard to virtual colonoscopy (VC) as compared with conventional colonoscopy (CC). Methods: Patients who were scheduled for colonoscopy for clinically indicated reasons underwent VC before CC; both procedures were performed on the same day. All endoscopic procedures were performed by senior gastroenterology fellows under attending supervision.

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