Original ArticleClinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types
Section snippets
Patients and methods
Included in the present study are a total of 367 SAs found in 355 (0.02%) of 15,656 patients (9396 men, 6260 women) examined from January 1992 until December 2001. Patients who did not have total colonoscopy and those with an established diagnosis of familial adenomatous polyposis or inflammatory bowel disease were excluded. All lesions were excised by EMR or electrosurgical snare polypectomy. Serrated adenomas were divided into two types based on their macroscopic appearances: polypoid (n = 240)
Results
The age of patients with polypoid SA ranged from 28 to 88 years with a mean of 59.7 (12.3) years; the age for those with superficial SA ranged from 29 to 74 years, with a mean of 60.8 (11.8) years. The difference in age between the two groups was not significant. The male:female gender ratio was significantly higher for polypoid SAs (187:53) than for superficial SAs (80:47). Polypoid SAs were located in the distal portion of the colorectum more frequently than superficial SAs (p<0.05 in a
Discussion
Some of the results of the present study differ from published data. That is, the male:female gender ratio observed for both polypoid and superficial SAs was higher than that previously reported.1 Superficial SAs were distributed comparatively equally in all parts of the colorectum, whereas polypoid SAs were predominant in the distal colorectum, as found in prior studies.1., 2., 3. It is possible that superficial SAs were not fully examined in prior investigations, which may account for the
Acknowledgements
We thank Dr. Shimamoto MD, PhD, in the department of pathology in our hospital for microscopic examinations and histologic diagnoses.
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